MRPL24

GENE INFORMATION

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Gene name

MRPL24 (HGNC Symbol)

Synonyms

MRP-L18

Description

mitochondrial ribosomal protein L24 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein which is more than twice the size of its E.coli counterpart (EcoL24). Sequence analysis identified two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q23.1

Chromosome location (bp)

156707095 - 156711382

Ensembl

ENSG00000143314 (version 73.37)

Entrez gene

79590

UniProt

Q96A35 (UniProt - Evidence at protein level)

neXtProt

NX_Q96A35

Antibodypedia

MRPL24 antibodies
 

PROTEIN VIEW

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MRPL24-001
 
MRPL24-002
 
MRPL24-003
 
MRPL24-004
 
MRPL24-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL24-001 ENSP00000354525
ENST00000361531
Q96A35
Show all »
Show » Show » 216 24.9 Yes 0
MRPL24-002 ENSP00000357194
ENST00000368211
Q96A35
Show all »
Show » Show » 216 24.9 Yes 0
MRPL24-003 ENSP00000406681
ENST00000412846
Q96A35
Show all »
Show » Show » 99 11.2 Yes 0
MRPL24-004 ENSP00000409803
ENST00000420938
Q96A35
Show all »
Show » Show » 68 7.7 Yes 0
MRPL24-005 ENSP00000411369
ENST00000434558
Q96A35
Show all »
Show » Show » 173 19.8 Yes 0