ABL2

GENE INFORMATION

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Gene name

ABL2 (HGNC Symbol)

Synonyms

ABLL, ARG

Description

c-abl oncogene 2, non-receptor tyrosine kinase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the Abelson family of nonreceptor tyrosine protein kinases. The protein is highly similar to the c-abl oncogene 1 protein, including the tyrosine kinase, SH2 and SH3 domains, and it plays a role in cytoskeletal rearrangements through its C-terminal F-actin- and microtubule-binding sequences. This gene is expressed in both normal and tumor cells, and is involved in translocation with the ets variant 6 gene in leukemia. Multiple alternatively spliced transcript variants encoding different protein isoforms have been found for this gene. [provided by RefSeq, Nov 2009]

Chromosome

1 (Chromosome progress)

Cytoband

q25.2

Chromosome location (bp)

179068462 - 179198819

Ensembl

ENSG00000143322 (version 73.37)

Entrez gene

27

UniProt

P42684 (UniProt - Evidence at protein level)

neXtProt

NX_P42684

Antibodypedia

ABL2 antibodies
 

PROTEIN VIEW

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ABL2-001
 
ABL2-002
 
ABL2-005
 
ABL2-006
 
ABL2-007
 
ABL2-008
 
ABL2-009
 
ABL2-010
 
ABL2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ABL2-001 ENSP00000427562
ENST00000502732
P42684
Show all »
Show » Show » 1182 128.3 No 0
ABL2-002 ENSP00000339209
ENST00000344730
P42684
Show all »
Show » Show » 1064 116.3 No 0
ABL2-005 ENSP00000423578
ENST00000512653
P42684
Show all »
Show » Show » 1167 126.7 No 0
ABL2-006 ENSP00000426831
ENST00000504405
P42684
Show all »
Show » Show » 1043 114.2 No 0
ABL2-007 ENSP00000375897
ENST00000392043
P42684
Show all »
Show » Show » 542 60.9 No 0
ABL2-008 ENSP00000356595
ENST00000367623
P42684
Show all »
Show » Show » 1161 126.2 No 0
ABL2-009 ENSP00000423413
ENST00000507173
P42684
Show all »
Show » Show » 1058 115.8 No 0
ABL2-010 ENSP00000424697
ENST00000511413
P42684
Show all »
Show » Show » 1079 117.9 No 0
ABL2-201 ENSP00000386152
ENST00000408940
P42684
Show all »
Show » Show » 1146 124.6 No 0