SETDB1

GENE INFORMATION

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Gene name

SETDB1 (HGNC Symbol)

Synonyms

ESET, KG1T, KIAA0067, KMT1E, TDRD21

Description

SET domain, bifurcated 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a histone methyltransferase which regulates histone methylation, gene silencing, and transcriptional repression. This gene has been identified as a target for treatment in Huntington Disease, given that gene silencing and transcription dysfunction likely play a role in the disease pathogenesis. Alternatively spliced transcript variants of this gene have been described.[provided by RefSeq, Jun 2011]

Chromosome

1 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

150898739 - 150937213

Ensembl

ENSG00000143379 (version 73.37)

Entrez gene

9869

UniProt

Q15047 (UniProt - Evidence at protein level)

neXtProt

NX_Q15047

Antibodypedia

SETDB1 antibodies
 

PROTEIN VIEW

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SETDB1-001
 
SETDB1-002
 
SETDB1-005
 
SETDB1-006
 
SETDB1-008
 
SETDB1-009
 
SETDB1-012
 
SETDB1-013
 
SETDB1-014
 
SETDB1-016
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SETDB1-001 ENSP00000271640
ENST00000271640
Q15047
Show all »
Show » Show » 1291 143.2 No 0
SETDB1-002 ENSP00000357958
ENST00000368962
Q15047
Show all »
Show » Show » 397 44.7 No 1
SETDB1-005 ENSP00000432348
ENST00000498193
E9PRF4
Show all »
Show » Show » 1259 139.4 No 0
SETDB1-006 ENSP00000435922
ENST00000525956
E9PS59
Show all »
Show » Show » 163 18.2 No 0
SETDB1-008 ENSP00000407831
ENST00000423081
Q15047
Show all »
Show » Show » 151 17.1 No 0
SETDB1-009 ENSP00000357959
ENST00000368963
Q15047
Show all »
Show » Show » 249 27.7 No 0
SETDB1-012 ENSP00000409379
ENST00000448029
B0QZE6
Show all »
Show » Show » 156 17.4 No 0
SETDB1-013 ENSP00000436148
ENST00000534805
E9PQM8
Show all »
Show » Show » 636 71 No 0
SETDB1-014 ENSP00000357965
ENST00000368969
Q15047
Show all »
Show » Show » 1290 143 No 0
SETDB1-016 ENSP00000357960
ENST00000368964
E9PAP1
Show all »
111 12.4 No 0