DYRK3

GENE INFORMATION

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Gene name

DYRK3 (HGNC Symbol)

Synonyms

hYAK3-2, RED, REDK

Description

dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3 (HGNC Symbol)

Entrez gene summary

This gene product belongs to the DYRK family of dual-specificity protein kinases that catalyze autophosphorylation on serine/threonine and tyrosine residues. The members of this family share structural similarity, however, differ in their substrate specificity, suggesting their involvement in different cellular functions. The encoded protein has been shown to autophosphorylate on tyrosine residue and catalyze phosphorylation of histones H3 and H2B in vitro. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q32.1

Chromosome location (bp)

206808881 - 206857764

Ensembl

ENSG00000143479 (version 73.37)

Entrez gene

8444

UniProt

O43781 (UniProt - Evidence at transcript level)

neXtProt

NX_O43781

Antibodypedia

DYRK3 antibodies
 

PROTEIN VIEW

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DYRK3-001
 
DYRK3-002
 
DYRK3-004
 
DYRK3-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DYRK3-001 ENSP00000356076
ENST00000367109
O43781
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Show » Show » 588 65.7 No 0
DYRK3-002 ENSP00000356075
ENST00000367108
O43781
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Show » Show » 568 64 No 0
DYRK3-004 ENSP00000356073
ENST00000367106
O43781
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Show » Show » 568 64 No 0
DYRK3-005 ENSP00000410187
ENST00000441486
Q5SY34
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Show » 243 27.6 No 0