RAB13

GENE INFORMATION

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Gene name

RAB13

Synonyms

Description

RAB13, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

This gene is a member of the Rab family of small G proteins and plays a role in regulating membrane trafficking between trans-Golgi network (TGN) and recycling endosomes (RE). The encoded protein is involved in the assembly of tight junctions, which are components of the apical junctional complex (AJC) of epithelial cells. The AJC plays a role in forming a barrier between luminal contents and the underlying tissue. Additional functions associated with the protein include endocytic recycling of occludin, regulation of epithelial cell scattering, neuronal regeneration and regulation of neurite outgrowth. Alternately spliced transcript variants have been observed for this gene. A pseudogene associated with this gene is located on chromosome 12. [provided by RefSeq, Jan 2013]

Chromosome

1 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

153954127 - 153958834

Ensembl

ENSG00000143545 (version 73.37)

Entrez gene

5872

UniProt

P51153 (UniProt - Evidence at protein level)

neXtProt

NX_P51153

Antibodypedia

RAB13 antibodies
 

PROTEIN VIEW

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RAB13-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RAB13-001 ENSP00000357564
ENST00000368575
P51153
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