CEP170

GENE INFORMATION

? »

Gene name

CEP170 (HGNC Symbol)

Synonyms

FAM68A, KAB, KIAA0470

Description

centrosomal protein 170kDa (HGNC Symbol)

Entrez gene summary

The product of this gene is a component of the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of this gene have been found, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q43

Chromosome location (bp)

243287730 - 243418650

Ensembl

ENSG00000143702 (version 73.37)

Entrez gene

9859

UniProt

Q5SW79 (UniProt - Evidence at protein level)

neXtProt

NX_Q5SW79

Antibodypedia

CEP170 antibodies
 

PROTEIN VIEW

? »
 
 
 « 
 
CEP170-001
 
CEP170-002
 
CEP170-003
 
CEP170-004
 
CEP170-006
 
CEP170-007
 
CEP170-008
 
CEP170-009
 
CEP170-010
 
CEP170-018
 
CEP170-019
 
CEP170-020
 
CEP170-025
 
CEP170-026
 
 » 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CEP170-001 ENSP00000355502
ENST00000366544
Q5SW79
Show all »
Show » 1486 164.5 No 0
CEP170-002 ENSP00000355501
ENST00000366543
Q5SW79
Show all »
Show » 1460 161.4 No 0
CEP170-003 ENSP00000355500
ENST00000366542
Q5SW79
Show all »
Show » 1584 175.3 No 0
CEP170-004 ENSP00000338161
ENST00000336415
E7EMW0
Show all »
Show » 1558 172 No 0
CEP170-006 ENSP00000430142
ENST00000490813
E7EWM2
Show all »
293 32.7 No 0
CEP170-007 ENSP00000427842
ENST00000481987
E7EMW0
Show all »
320 35.5 No 0
CEP170-008 ENSP00000428777
ENST00000461671
119 13.1 No 0
CEP170-009 ENSP00000427843
ENST00000464936
E5RG47
Show all »
175 19.9 No 0
CEP170-010 ENSP00000430112
ENST00000492145
E5RGW7
Show all »
103 11.5 No 0
CEP170-018 ENSP00000428400
ENST00000522995
E5RIH6
Show all »
Show » 88 10.1 No 0
CEP170-019 ENSP00000427944
ENST00000522191
E5RFU8
Show all »
Show » 133 15.2 No 0
CEP170-020 ENSP00000428183
ENST00000523424
E5RJT5
Show all »
Show » 111 12.7 No 0
CEP170-025 ENSP00000428996
ENST00000522895
Show » 173 19.8 No 1
CEP170-026 ENSP00000394002
ENST00000413359
H0Y4T4
Show all »
263 29.1 No 0