CDC42BPA

GENE INFORMATION

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Gene name

CDC42BPA (HGNC Symbol)

Synonyms

FLJ23347, KIAA0451, MRCK, MRCKA, PK428

Description

CDC42 binding protein kinase alpha (DMPK-like) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a member of the Serine/Threonine protein kinase family. This kinase contains multiple functional domains. Its kinase domain is highly similar to that of the myotonic dystrophy protein kinase (DMPK). This kinase also contains a Rac interactive binding (CRIB) domain, and has been shown to bind CDC42. It may function as a CDC42 downstream effector mediating CDC42 induced peripheral actin formation, and promoting cytoskeletal reorganization. Multiple alternatively spliced transcript variants have been described, and the full-length nature of two of them has been reported. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q42.13

Chromosome location (bp)

227177566 - 227506175

Ensembl

ENSG00000143776 (version 73.37)

Entrez gene

8476

UniProt

Q5VT25 (UniProt - Evidence at protein level)

neXtProt

NX_Q5VT25

Antibodypedia

CDC42BPA antibodies
 

PROTEIN VIEW

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 « 
 
CDC42BPA-001
 
CDC42BPA-002
 
CDC42BPA-003
 
CDC42BPA-004
 
CDC42BPA-005
 
CDC42BPA-006
 
CDC42BPA-007
 
CDC42BPA-201
 
CDC42BPA-202
 
CDC42BPA-203
 
CDC42BPA-204
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CDC42BPA-001 ENSP00000355731
ENST00000366769
Q5VT25
Show all »
Show » Show » 1719 195.9 No 0
CDC42BPA-002 ENSP00000355729
ENST00000366767
Q5VT25
Show all »
Show » Show » 1638 186.1 No 0
CDC42BPA-003 ENSP00000355727
ENST00000366765
Q5VT25
Show all »
Show » Show » 1732 197.3 No 0
CDC42BPA-004 ENSP00000401051
ENST00000442054
Show » 1048 117.7 No 0
CDC42BPA-005 ENSP00000408165
ENST00000441725
Show » 728 81.6 No 0
CDC42BPA-006 ENSP00000415388
ENST00000448940
Show » 984 109.9 No 0
CDC42BPA-007 ENSP00000407120
ENST00000429440
Q9H5K7
Show all »
Show » 546 61.7 No 0
CDC42BPA-201 ENSP00000335341
ENST00000334218
Q5VT25
Show all »
Show » Show » 1781 202.8 No 0
CDC42BPA-202 ENSP00000355726
ENST00000366764
Q5VT25
Show all »
Show » Show » 1691 193 No 0
CDC42BPA-203 ENSP00000355728
ENST00000366766
Q5VT25
Show all »
Show » Show » 1754 199.8 No 0
CDC42BPA-204 ENSP00000443275
ENST00000535525
F5H5N0
Show all »
Show » Show » 1699 193.6 No 0