PYCR2

GENE INFORMATION

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Gene name

PYCR2 (HGNC Symbol)

Synonyms

P5CR2

Description

Pyrroline-5-carboxylate reductase family, member 2 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

1

Cytoband

q42.12

Chromosome location (bp)

226107578 - 226111978

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000143811 (version 75.37)

Entrez gene

102466270

UniProt

Q96C36 (UniProt - Evidence at protein level)

neXtProt

NX_Q96C36

Antibodypedia

PYCR2 antibodies
 

PROTEIN VIEW

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PYCR2-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PYCR2-001 ENSP00000342502
ENST00000343818
Q96C36
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