LBR

GENE INFORMATION

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Gene name

LBR (HGNC Symbol)

Synonyms

DHCR14B, TDRD18

Description

lamin B receptor (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the ERG4/ERG24 family. It localized in the nuclear envelope inner membrane and anchors the lamina and the heterochromatin to the membrane. It may mediate interaction between chromatin and lamin B. Mutations of this gene has been associated with autosomal recessive HEM/Greenberg skeletal dysplasia. Alternative splicing occurs at this locus and two transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q42.12

Chromosome location (bp)

225589204 - 225616627

Ensembl

ENSG00000143815 (version 73.37)

Entrez gene

3930

UniProt

Q14739 (UniProt - Evidence at protein level)

neXtProt

NX_Q14739

Antibodypedia

LBR antibodies
 

PROTEIN VIEW

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LBR-001
 
LBR-002
 
LBR-003
 
LBR-006
 
LBR-007
 
LBR-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

LBR-001 ENSP00000272163
ENST00000272163
Q14739
Show all »
Show » Show » 615 70.7 No 9
LBR-002 ENSP00000388059
ENST00000425080
C9JXK0
Show all »
Show » 213 24.3 No 0
LBR-003 ENSP00000416554
ENST00000421383
C9JES9
Show all »
Show » 51 5.9 No 0
LBR-006 ENSP00000415428
ENST00000441022
Show » Show » 107 12.9 No 1
LBR-007 ENSP00000397817
ENST00000424022
H7C108
Show all »
Show » Show » 128 14.7 No 3
LBR-201 ENSP00000339883
ENST00000338179
Q14739
Show all »
Show » Show » 615 70.7 No 9