EPHX1

GENE INFORMATION

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Gene name

EPHX1 (HGNC Symbol)

Synonyms

EPHX

Description

epoxide hydrolase 1, microsomal (xenobiotic) (HGNC Symbol)

Entrez gene summary

Epoxide hydrolase is a critical biotransformation enzyme that converts epoxides from the degradation of aromatic compounds to trans-dihydrodiols which can be conjugated and excreted from the body. Epoxide hydrolase functions in both the activation and detoxification of epoxides. Mutations in this gene cause preeclampsia, epoxide hydrolase deficiency or increased epoxide hydrolase activity. Alternatively spliced transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Dec 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q42.12

Chromosome location (bp)

225997794 - 226033260

Ensembl

ENSG00000143819 (version 73.37)

Entrez gene

2052

UniProt

P07099 (UniProt - Evidence at protein level)

neXtProt

NX_P07099

Antibodypedia

EPHX1 antibodies
 

PROTEIN VIEW

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EPHX1-001
 
EPHX1-002
 
EPHX1-003
 
EPHX1-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHX1-001 ENSP00000355802
ENST00000366837
P07099
Show all »
Show » Show » 455 52.9 No 0
EPHX1-002 ENSP00000398491
ENST00000445856
B1AQP9
Show all »
Show » Show » 161 19.3 No 0
EPHX1-003 ENSP00000408469
ENST00000448202
B1AQP8
Show all »
Show » Show » 136 16.4 No 0
EPHX1-201 ENSP00000272167
ENST00000272167
P07099
Show all »
Show » Show » 455 52.9 No 0