SNRNP200

GENE INFORMATION

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Gene name

SNRNP200 (HGNC Symbol)

Synonyms

ASCC3L1, BRR2, HELIC2, KIAA0788, RP33, U5-200KD

Description

small nuclear ribonucleoprotein 200kDa (U5) (HGNC Symbol)

Entrez gene summary

Pre-mRNA splicing is catalyzed by the spliceosome, a complex of specialized RNA and protein subunits that removes introns from a transcribed pre-mRNA segment. The spliceosome consists of small nuclear RNA proteins (snRNPs) U1, U2, U4, U5 and U6, together with approximately 80 conserved proteins. U5 snRNP contains nine specific proteins. This gene encodes one of the U5 snRNP-specific proteins. This protein belongs to the DEXH-box family of putative RNA helicases. It is a core component of U4/U6-U5 snRNPs and appears to catalyze an ATP-dependent unwinding of U4/U6 RNA duplices. Mutations in this gene cause autosomal-dominant retinitis pigmentosa. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined. [provided by RefSeq, Mar 2010]

Chromosome

2 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

96940074 - 96971297

Ensembl

ENSG00000144028 (version 73.37)

Entrez gene

23020

UniProt

O75643 (UniProt - Evidence at protein level)

neXtProt

NX_O75643

Antibodypedia

SNRNP200 antibodies
 

PROTEIN VIEW

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SNRNP200-001
 
SNRNP200-006
 
SNRNP200-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SNRNP200-001 ENSP00000317123
ENST00000323853
O75643
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Show » Show » 2136 244.5 No 0
SNRNP200-006 ENSP00000387870
ENST00000429650
B4E0P5
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Show » Show » 595 67.8 No 0
SNRNP200-201 ENSP00000326937
ENST00000349783
C9JAQ9
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Show » 625 71.5 No 0