MRPS5

GENE INFORMATION

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Gene name

MRPS5 (HGNC Symbol)

Synonyms

MRP-S5, S5mt

Description

mitochondrial ribosomal protein S5 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to this gene are found on chromosomes 4q, 5q, and 18q. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q11.1

Chromosome location (bp)

95752952 - 95815179

Ensembl

ENSG00000144029 (version 73.37)

Entrez gene

64969

UniProt

P82675 (UniProt - Evidence at protein level)

neXtProt

NX_P82675

Antibodypedia

MRPS5 antibodies
 

PROTEIN VIEW

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MRPS5-001
 
MRPS5-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPS5-001 ENSP00000272418
ENST00000272418
P82675
Show all »
Show » Show » 430 48 No 0
MRPS5-002 ENSP00000341660
ENST00000345084
P82675
Show all »
Show » Show » 251 27.8 No 0