ACKR3

GENE INFORMATION

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Gene name

ACKR3 (HGNC Symbol)

Synonyms

CMKOR1, CXCR7, GPR159, RDC1

Description

atypical chemokine receptor 3 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the G-protein coupled receptor family. Although this protein was earlier thought to be a receptor for vasoactive intestinal peptide (VIP), it is now considered to be an orphan receptor, in that its endogenous ligand has not been identified. The protein is also a coreceptor for human immunodeficiency viruses (HIV). Translocations involving this gene and HMGA2 on chromosome 12 have been observed in lipomas. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q37.3

Chromosome location (bp)

237476430 - 237491001

Ensembl

ENSG00000144476 (version 73.37)

Entrez gene

57007

UniProt

P25106 (UniProt - Evidence at protein level)

neXtProt

NX_P25106

Antibodypedia

ACKR3 antibodies
 

PROTEIN VIEW

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ACKR3-001
 
ACKR3-002
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ACKR3-001 ENSP00000272928
ENST00000272928
P25106
Show all »
Show » Show » 362 41.5 No 7
ACKR3-002 ENSP00000405945
ENST00000447924
Show » Show » 211 24.2 No 4