AGTR1

GENE INFORMATION

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Gene name

AGTR1 (HGNC Symbol)

Synonyms

AG2S, AGTR1A, AGTR1B, AT1, AT1B, AT2R1, AT2R1A, AT2R1B, HAT1R

Description

angiotensin II receptor, type 1 (HGNC Symbol)

Entrez gene summary

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene. [provided by RefSeq, Jul 2012]

Chromosome

3 (Chromosome progress)

Cytoband

q24

Chromosome location (bp)

148415571 - 148460795

Ensembl

ENSG00000144891 (version 73.37)

Entrez gene

185

UniProt

P30556 (UniProt - Evidence at protein level)

neXtProt

NX_P30556

Antibodypedia

AGTR1 antibodies
 

PROTEIN VIEW

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AGTR1-001
 
AGTR1-002
 
AGTR1-003
 
AGTR1-005
 
AGTR1-006
 
AGTR1-007
 
AGTR1-201
 
AGTR1-202
 
AGTR1-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

AGTR1-001 ENSP00000273430
ENST00000349243
P30556
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Show » Show » 359 41.1 No 7
AGTR1-002 ENSP00000419422
ENST00000497524
P30556
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Show » Show » 359 41.1 No 7
AGTR1-003 ENSP00000385612
ENST00000404754
P30556
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Show » Show » 359 41.1 No 7
AGTR1-005 ENSP00000419783
ENST00000475347
P30556
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Show » Show » 359 41.1 No 7
AGTR1-006 ENSP00000418084
ENST00000474935
P30556
Show all »
Show » Show » 359 41.1 No 7
AGTR1-007 ENSP00000418851
ENST00000461609
P30556
Show all »
Show » Show » 359 41.1 No 7
AGTR1-201 ENSP00000385641
ENST00000402260
P30556
Show all »
Show » Show » 359 41.1 No 7
AGTR1-202 ENSP00000398832
ENST00000418473
P30556
Show all »
Show » Show » 359 41.1 No 7
AGTR1-203 ENSP00000443186
ENST00000542281
P30556
Show all »
Show » Show » 359 41.1 No 7