ALDH1L1

GENE INFORMATION

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Gene name

ALDH1L1 (HGNC Symbol)

Synonyms

10-fTHF, FTHFD

Description

aldehyde dehydrogenase 1 family, member L1 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene catalyzes the conversion of 10-formyltetrahydrofolate, nicotinamide adenine dinucleotide phosphate (NADP+), and water to tetrahydrofolate, NADPH, and carbon dioxide. The encoded protein belongs to the aldehyde dehydrogenase family. Loss of function or expression of this gene is associated with decreased apoptosis, increased cell motility, and cancer progression. There is an antisense transcript that overlaps on the opposite strand with this gene locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2012]

Chromosome

3 (Chromosome progress)

Cytoband

q21.3

Chromosome location (bp)

125822412 - 125916837

Ensembl

ENSG00000144908 (version 73.37)

Entrez gene

10840

UniProt

O75891 (UniProt - Evidence at protein level)

neXtProt

NX_O75891

Antibodypedia

ALDH1L1 antibodies
 

PROTEIN VIEW

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 « 
 
ALDH1L1-001
 
ALDH1L1-002
 
ALDH1L1-004
 
ALDH1L1-005
 
ALDH1L1-006
 
ALDH1L1-007
 
ALDH1L1-008
 
ALDH1L1-009
 
ALDH1L1-014
 
ALDH1L1-015
 
ALDH1L1-016
 
ALDH1L1-201
 
ALDH1L1-202
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALDH1L1-001 ENSP00000273450
ENST00000273450
O75891
Show all »
Show » Show » 912 99.8 No 0
ALDH1L1-002 ENSP00000377083
ENST00000393434
O75891
Show all »
Show » Show » 902 98.8 No 0
ALDH1L1-004 ENSP00000418711
ENST00000490367
C9IZ36
Show all »
Show » 177 19.6 No 0
ALDH1L1-005 ENSP00000419955
ENST00000488356
C9JY00
Show all »
Show » 157 17.3 No 0
ALDH1L1-006 ENSP00000419826
ENST00000460368
C9JYZ6
Show all »
Show » 168 18.6 No 0
ALDH1L1-007 ENSP00000420293
ENST00000472186
O75891
Show all »
Show » Show » 902 98.8 No 0
ALDH1L1-008 ENSP00000419448
ENST00000473607
F2Z324
Show all »
Show » 47 5.2 No 0
ALDH1L1-009 ENSP00000418905
ENST00000493803
F8WC34
Show all »
Show » 81 9 No 0
ALDH1L1-014 ENSP00000426713
ENST00000511283
F2Z324
Show all »
Show » 47 5.2 No 0
ALDH1L1-015 ENSP00000426594
ENST00000509952
D6RFJ7
Show all »
Show » 100 11 No 0
ALDH1L1-016 ENSP00000395881
ENST00000452905
O75891
Show all »
Show » Show » 801 87.6 No 0
ALDH1L1-201 ENSP00000377081
ENST00000393431
Q8TBP8
Show all »
Show » Show » 505 55.4 No 0
ALDH1L1-202 ENSP00000414126
ENST00000455064
B4DGC8
Show all »
Show » 160 17.4 No 0