CORIN

GENE INFORMATION

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Gene name

CORIN (HGNC Symbol)

Synonyms

ATC2, CRN, Lrp4, PRSC, TMPRSS10

Description

corin, serine peptidase (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the type II transmembrane serine protease class of the trypsin superfamily. Members of this family are composed of multiple structurally distinct domains. The encoded protein converts pro-atrial natriuretic peptide to biologically active atrial natriuretic peptide, a cardiac hormone that regulates blood volume and pressure. This protein may also function as a pro-brain-type natriuretic peptide convertase. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2013]

Chromosome

4 (Chromosome progress)

Cytoband

p12

Chromosome location (bp)

47596015 - 47840123

Ensembl

ENSG00000145244 (version 73.37)

Entrez gene

10699

UniProt

Q9Y5Q5 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y5Q5

Antibodypedia

CORIN antibodies
 

PROTEIN VIEW

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CORIN-001
 
CORIN-003
 
CORIN-005
 
CORIN-009
 
CORIN-010
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CORIN-001 ENSP00000273857
ENST00000273857
Q9Y5Q5
Show all »
Show » Show » 1042 116.5 No 1
CORIN-003 ENSP00000425401
ENST00000505909
J3KR90
Show all »
Show » Show » 1005 112.4 No 1
CORIN-005 ENSP00000424212
ENST00000502252
J3KR88
Show all »
Show » Show » 975 109.2 No 1
CORIN-009 ENSP00000425597
ENST00000508498
E7EQE7
Show all »
Show » Show » 903 101.5 No 0
CORIN-010 ENSP00000423216
ENST00000504584
J3KR83
Show all »
Show » Show » 734 81.8 No 1