USP53

CANCER ATLAS

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Gene description

Ubiquitin specific peptidase 53

Protein class

Enzymes, Predicted intracellular proteins

Protein evidence

Evidence at protein level
 
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer

STAINING SUMMARY

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HPA035844
 
 
HPA035845
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Tissue

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 
 

Staining summary

Fraction of cells in several gliomas along with occasional cases of squamous cell carcinomas of skin, breast, ovarian and pancreatic cancers showed moderate to strong cytoplasmic and/or nuclear positivity. Remaining cancer tissues were weakly stained or generally negative.
 

Level of antibody staining/expression





High
Medium
Low
Not detected