GZMA

GENE INFORMATION

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Gene name

GZMA (HGNC Symbol)

Synonyms

CTLA3, HFSP

Description

granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) (HGNC Symbol)

Entrez gene summary

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq, Jul 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q11.2

Chromosome location (bp)

54398476 - 54406080

Ensembl

ENSG00000145649 (version 73.37)

Entrez gene

3001

UniProt

P12544 (UniProt - Evidence at protein level)

neXtProt

NX_P12544

Antibodypedia

GZMA antibodies
 

PROTEIN VIEW

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GZMA-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GZMA-001 ENSP00000274306
ENST00000274306
P12544
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