ARHGAP26

GENE INFORMATION

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Gene name

ARHGAP26 (HGNC Symbol)

Synonyms

GRAF, KIAA0621, OPHN1L, OPHN1L1

Description

Rho GTPase activating protein 26 (HGNC Symbol)

Entrez gene summary

Interaction of a cell with the extracellular matrix triggers integrin cell surface receptors to begin signaling cascades that regulate the organization of the actin-cytoskeleton. One of the proteins involved in these cascades is focal adhesion kinase. The protein encoded by this gene is a GTPase activating protein that binds to focal adhesion kinase and mediates the activity of the GTP binding proteins RhoA and Cdc42. Defects in this gene are a cause of juvenile myelomonocytic leukemia (JMML). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

Chromosome

5 (Chromosome progress)

Cytoband

q31.3

Chromosome location (bp)

142149949 - 142608576

Ensembl

ENSG00000145819 (version 73.37)

Entrez gene

23092

UniProt

Q9UNA1 (UniProt - Evidence at protein level)

neXtProt

NX_Q9UNA1

Antibodypedia

ARHGAP26 antibodies
 

PROTEIN VIEW

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 « 
 
ARHGAP26-001
 
ARHGAP26-008
 
ARHGAP26-009
 
ARHGAP26-012
 
ARHGAP26-013
 
ARHGAP26-014
 
ARHGAP26-015
 
ARHGAP26-018
 
ARHGAP26-019
 
ARHGAP26-020
 
ARHGAP26-021
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ARHGAP26-001 ENSP00000274498
ENST00000274498
Q9UNA1
Show all »
Show » Show » 814 92.2 No 0
ARHGAP26-008 ENSP00000367243
ENST00000378004
Q9UNA1
Show all »
Show » Show » 759 86.2 No 0
ARHGAP26-009 ENSP00000392186
ENST00000443045
H7BZZ0
Show all »
Show » Show » 97 10.9 No 0
ARHGAP26-012 ENSP00000389137
ENST00000421521
Show » Show » 154 16.2 No 1
ARHGAP26-013 ENSP00000403388
ENST00000425417
Show » Show » 98 10.1 No 0
ARHGAP26-014 ENSP00000367252
ENST00000378013
F8W8N5
Show all »
Show » 166 19.5 No 0
ARHGAP26-015 ENSP00000411571
ENST00000451259
C9J6V4
Show all »
Show » Show » 91 10.2 No 0
ARHGAP26-018 ENSP00000400565
ENST00000424007
H7C1J1
Show all »
Show » 127 13.9 No 0
ARHGAP26-019 ENSP00000413283
ENST00000419676
H7C3P8
Show all »
Show » 127 14 No 0
ARHGAP26-020 ENSP00000416889
ENST00000418236
D9ZGG7
Show all »
Show » Show » 294 32.8 No 0
ARHGAP26-021 ENSP00000393276
ENST00000443674
Q8NFJ1
Show all »
Show » Show » 388 42.9 No 0