NHP2

GENE INFORMATION

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Gene name

NHP2 (HGNC Symbol)

Synonyms

FLJ20479, NOLA2

Description

NHP2 ribonucleoprotein (HGNC Symbol)

Entrez gene summary

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nhp2p. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2008]

Chromosome

5 (Chromosome progress)

Cytoband

q35.3

Chromosome location (bp)

177576461 - 177580968

Ensembl

ENSG00000145912 (version 73.37)

Entrez gene

55651

UniProt

Q9NX24 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NX24

Antibodypedia

NHP2 antibodies
 

PROTEIN VIEW

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NHP2-001
 
NHP2-002
 
NHP2-003
 
NHP2-004
 
NHP2-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

NHP2-001 ENSP00000274606
ENST00000274606
Q9NX24
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Show » Show » 153 17.2 No 0
NHP2-002 ENSP00000366276
ENST00000314397
J3QSY4
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Show » 90 10.1 No 0
NHP2-003 ENSP00000423803
ENST00000514354
D6RCB9
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Show » Show » 135 15.2 No 0
NHP2-004 ENSP00000431126
ENST00000502263
H0YC83
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85 9.6 No 0
NHP2-005 ENSP00000423849
ENST00000511078
D6RC52
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Show » 132 15 No 0