TPBG

GENE INFORMATION

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Gene name

TPBG (HGNC Symbol)

Synonyms

5T4, 5T4-AG

Description

trophoblast glycoprotein (HGNC Symbol)

Entrez gene summary

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein. [provided by RefSeq, Oct 2009]

Chromosome

6 (Chromosome progress)

Cytoband

q14.1

Chromosome location (bp)

83072923 - 83080545

Ensembl

ENSG00000146242 (version 73.37)

Entrez gene

7162

UniProt

Q13641 (UniProt - Evidence at protein level)

neXtProt

NX_Q13641

Antibodypedia

TPBG antibodies
 

PROTEIN VIEW

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TPBG-001
 
TPBG-201
 
TPBG-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

TPBG-001 ENSP00000358765
ENST00000369750
Q13641
Show all »
Show » Show » 420 46 Yes 1
TPBG-201 ENSP00000441219
ENST00000535040
Q13641
Show all »
Show » Show » 420 46 Yes 1
TPBG-202 ENSP00000440049
ENST00000543496
Q13641
Show all »
Show » Show » 420 46 Yes 1