IGFBP1

GENE INFORMATION

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Gene name

IGFBP1 (HGNC Symbol)

Synonyms

AFBP, hIGFBP-1, IBP1, IGF-BP25, PP12

Description

insulin-like growth factor binding protein 1 (HGNC Symbol)

Entrez gene summary

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

p12.3

Chromosome location (bp)

45927956 - 45933267

Ensembl

ENSG00000146678 (version 73.37)

Entrez gene

3484

UniProt

P08833 (UniProt - Evidence at protein level)

neXtProt

NX_P08833

Antibodypedia

IGFBP1 antibodies
 

PROTEIN VIEW

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IGFBP1-001
 
IGFBP1-002
 
IGFBP1-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IGFBP1-001 ENSP00000275525
ENST00000275525
P08833
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Show » Show » 259 27.9 Yes 0
IGFBP1-002 ENSP00000413511
ENST00000457280
C9JXF9
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Show » Show » 257 27.7 Yes 0
IGFBP1-003 ENSP00000417069
ENST00000468955
C9J6H2
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Show » Show » 216 22.9 Yes 0