MDH2

GENE INFORMATION

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Gene name

MDH2

Synonyms

Description

malate dehydrogenase 2, NAD (mitochondrial) (HGNC Symbol)

Entrez gene summary

Malate dehydrogenase catalyzes the reversible oxidation of malate to oxaloacetate, utilizing the NAD/NADH cofactor system in the citric acid cycle. The protein encoded by this gene is localized to the mitochondria and may play pivotal roles in the malate-aspartate shuttle that operates in the metabolic coordination between cytosol and mitochondria. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2013]

Chromosome

7 (Chromosome progress)

Cytoband

q11.23

Chromosome location (bp)

75677369 - 75696826

Ensembl

ENSG00000146701 (version 73.37)

Entrez gene

4191

UniProt

P40926 (UniProt - Evidence at protein level)

neXtProt

NX_P40926

Antibodypedia

MDH2 antibodies
 

PROTEIN VIEW

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MDH2-001
 
MDH2-002
 
MDH2-003
 
MDH2-004
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MDH2-001 ENSP00000327070
ENST00000315758
P40926
Show all »
Show » Show » 338 35.5 No 0
MDH2-002 ENSP00000408649
ENST00000432020
E9PDB2
Show all »
Show » Show » 296 30.9 No 0
MDH2-003 ENSP00000475583
ENST00000461263
28 2.9 No 0
MDH2-004 ENSP00000416929
ENST00000443006
G3XAL0
Show all »
Show » 231 24.6 No 0