EPHA1

GENE INFORMATION

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Gene name

EPHA1 (HGNC Symbol)

Synonyms

EPH, EPHT, EPHT1

Description

EPH receptor A1 (HGNC Symbol)

Entrez gene summary

This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene is expressed in some human cancer cell lines and has been implicated in carcinogenesis. [provided by RefSeq, Jul 2008]

Chromosome

7 (Chromosome progress)

Cytoband

q34

Chromosome location (bp)

143087382 - 143105985

Ensembl

ENSG00000146904 (version 73.37)

Entrez gene

2041

UniProt

P21709 (UniProt - Evidence at protein level)

neXtProt

NX_P21709

Antibodypedia

EPHA1 antibodies
 

PROTEIN VIEW

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EPHA1-001
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EPHA1-001 ENSP00000275815
ENST00000275815
P21709
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