CCNB3

GENE INFORMATION

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Gene name

CCNB3

Synonyms

Description

Cyclin B3 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

X

Cytoband

p11.22

Chromosome location (bp)

49967364 - 50094909

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147082 (version 75.37)

Entrez gene

85417

UniProt

Q8WWL7 (UniProt - Evidence at protein level)

neXtProt

NX_Q8WWL7

Antibodypedia

CCNB3 antibodies
 

PROTEIN VIEW

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CCNB3-001
 
CCNB3-002
 
CCNB3-003
 
CCNB3-201
 
CCNB3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCNB3-001 ENSP00000365210
ENST00000376042
Q8WWL7
Show all »
Show » Show » 1395 157.9 No 0
CCNB3-002 ENSP00000365206
ENST00000376038
Q8WWL7
Show all »
Show » Show » 291 33.3 No 0
CCNB3-003 ENSP00000431645
ENST00000476167
Q8WWL7
Show all »
Show » Show » 111 12.2 No 0
CCNB3-201 ENSP00000276014
ENST00000276014
Q8WWL7
Show all »
Show » Show » 1395 157.9 No 0
CCNB3-202 ENSP00000338682
ENST00000348603
Q8WWL7
Show all »
Show » Show » 291 33.3 No 0