FBXO25

GENERAL INFORMATION

? »

Gene name

FBXO25

Gene description

F-box protein 25

Protein class

Disease related genes
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

5
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Expressed in all
GTEx:Tissue enriched (testis)

Protein evidence

Evidence at protein level

ANTIBODY RELIABILITY

? »

Data reliability

Pending normal tissue annotation.
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A


PROTEIN EXPRESSION OVERVIEW

? »
Pending normal tissue annotation.


RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enriched (testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

FBXO25 (HGNC Symbol)

Synonyms

FBX25

Description

F-box protein 25 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

8

Cytoband

p23.3

Chromosome location (bp)

406428 - 477967

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000147364 (version 78.38)

Entrez gene

26260

UniProt

Q8TCJ0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TCJ0

Antibodypedia

FBXO25 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000276326
 
ENST00000350302
 
ENST00000352684
 
ENST00000382824
 
ENST00000518240
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FBXO25-001 ENSP00000372274
ENST00000382824
Q8TCJ0
Show all »
Show » Show » 367 43.3 No 0
FBXO25-002 ENSP00000342077
ENST00000350302
Q8TCJ0
Show all »
Show » Show » 358 42.2 No 0
FBXO25-003 ENSP00000276326
ENST00000276326
Q8TCJ0
Show all »
Show » Show » 291 34.1 No 0
FBXO25-004 ENSP00000428872
ENST00000518240
E5RFH9
Show all »
Show » 125 15.1 No 0
FBXO25-201 ENSP00000341345
ENST00000352684
Q8TCJ0
Show all »
Show » Show » 291 34.1 No 0