RPL10

GENE INFORMATION

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Gene name

RPL10 (HGNC Symbol)

Synonyms

DXS648, DXS648E, FLJ23544, L10, NOV, QM

Description

ribosomal protein L10 (HGNC Symbol)

Entrez gene summary

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L10E family of ribosomal proteins. It is located in the cytoplasm. In vitro studies have shown that the chicken protein can bind to c-Jun and can repress c-Jun-mediated transcriptional activation, but these activities have not been demonstrated in vivo. This gene was initially identified as a candidate for a Wilms tumor suppressor gene, but later studies determined that this gene is not involved in the suppression of Wilms tumor. This gene has been referred to as 'laminin receptor homolog' because a chimeric transcript consisting of sequence from this gene and sequence from the laminin receptor gene was isolated; however, it is not believed that this gene encodes a laminin receptor. Alternative splicing results in multiple transcript variants. This gene also uses multiple polyA signals, with the 3'-most polyA signal overlapping the deoxyribonuclease I-like 1 gene on the opposite strand. This gene is co-transcribed with the small nucleolar RNA gene U70, which is located in its fifth intron. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Feb 2012]

Chromosome

X (Chromosome progress)

Cytoband

q28

Chromosome location (bp)

153618315 - 153637504

Ensembl

ENSG00000147403 (version 73.37)

Entrez gene

6134

UniProt

P27635 (UniProt - Evidence at protein level)

neXtProt

NX_P27635

Antibodypedia

RPL10 antibodies
 

PROTEIN VIEW

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RPL10-001
 
RPL10-008
 
RPL10-009
 
RPL10-011
 
RPL10-015
 
RPL10-017
 
RPL10-018
 
RPL10-019
 
RPL10-020
 
RPL10-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

RPL10-001 ENSP00000341730
ENST00000344746
P27635
Show all »
Show » Show » 214 24.6 No 0
RPL10-008 ENSP00000358832
ENST00000369817
P27635
Show all »
Show » Show » 214 24.6 No 0
RPL10-009 ENSP00000395025
ENST00000458500
A6QRI9
Show all »
Show » 181 20.2 No 0
RPL10-011 ENSP00000385621
ENST00000406022
F8W7C6
Show all »
Show » 163 18.6 No 0
RPL10-015 ENSP00000388600
ENST00000436473
Show » 201 23.1 No 0
RPL10-017 ENSP00000406125
ENST00000451365
B8A6G2
Show all »
Show » 108 12.3 No 0
RPL10-018 ENSP00000405064
ENST00000427682
H7C2C5
Show all »
Show » 131 14.6 No 0
RPL10-019 ENSP00000407754
ENST00000449494
H7C2U2
Show all »
Show » 28 3.1 No 0
RPL10-020 ENSP00000398047
ENST00000428169
H7C123
Show all »
Show » 91 10 No 0
RPL10-201 ENSP00000413436
ENST00000424325
P27635
Show all »
Show » Show » 214 24.6 No 0