SHC3

GENERAL INFORMATION

? »

Gene name

SHC3

Gene description

SHC (Src homology 2 domain containing) transforming protein 3

Protein class

Plasma proteins
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (adrenal gland, cerebral cortex)
GTEx:Tissue enhanced (cerebral cortex)

Protein evidence

Evidence at protein level

Protein localization

General cytoplasmic expression with additional nuclear expression in several tissues.

ANTIBODY RELIABILITY

? »

Data reliability
description

Antibody staining not consistent with RNA expression data.

Data reliability

Uncertain based on 1 antibody.
HPA046656
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (adrenal gland, cerebral cortex)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex)

Organ

Expression



GENE INFORMATION

? »

Gene name

SHC3 (HGNC Symbol)

Synonyms

N-Shc, NSHC, SHCC

Description

SHC (Src homology 2 domain containing) transforming protein 3 (HGNC Symbol)

Entrez gene summary

Chromosome

9

Cytoband

q22.1

Chromosome location (bp)

89013145 - 89178767

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148082 (version 78.38)

Entrez gene

53358

UniProt

Q92529 (UniProt - Evidence at protein level)

neXtProt

NX_Q92529

Antibodypedia

SHC3 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000375831
 
ENST00000375835
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SHC3-001 ENSP00000364995
ENST00000375835
Q92529
Show all »
Show » Show » 594 64.1 No 0
SHC3-002 ENSP00000364991
ENST00000375831
Q5T7I8
Show all »
Show » Show » 105 11.5 No 0