CACNA1B

GENE INFORMATION

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Gene name

CACNA1B (HGNC Symbol)

Synonyms

CACNL1A5, CACNN, Cav2.2

Description

calcium channel, voltage-dependent, N type, alpha 1B subunit (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is the pore-forming subunit of an N-type voltage-dependent calcium channel, which controls neurotransmitter release from neurons. The encoded protein forms a complex with alpha-2, beta, and delta subunits to form the high-voltage activated channel. This channel is sensitive to omega-conotoxin-GVIA and omega-agatoxin-IIIA but insensitive to dihydropyridines. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2011]

Chromosome

9 (Chromosome progress)

Cytoband

q34.3

Chromosome location (bp)

140772241 - 141019076

Ensembl

ENSG00000148408 (version 73.37)

Entrez gene

774

UniProt

Q00975 (UniProt - Evidence at protein level)

neXtProt

NX_Q00975

Antibodypedia

CACNA1B antibodies
 

PROTEIN VIEW

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 « 
 
CACNA1B-001
 
CACNA1B-002
 
CACNA1B-003
 
CACNA1B-004
 
CACNA1B-005
 
CACNA1B-201
 
CACNA1B-202
 
CACNA1B-203
 
CACNA1B-204
 
CACNA1B-205
 
CACNA1B-206
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CACNA1B-001 ENSP00000360423
ENST00000371372
Q00975
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Show » Show » 2339 262.5 No >9
CACNA1B-002 ENSP00000277551
ENST00000277551
B1AQK4
Show all »
Show » Show » 2237 251.7 No >9
CACNA1B-003 ENSP00000360414
ENST00000371363
B1AQK6
Show all »
Show » Show » 2337 262.3 No >9
CACNA1B-004 ENSP00000413042
ENST00000413253
Q5JRE4
Show all »
Show » Show » 165 19 Yes 1
CACNA1B-005 ENSP00000360408
ENST00000371357
B1AQK7
Show all »
Show » Show » 2338 262.3 No >9
CACNA1B-201 ENSP00000277549
ENST00000277549
E9PDR3
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Show » Show » 1533 171.6 No >9
CACNA1B-202 ENSP00000277550
ENST00000277550
Q9HAT6
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101 11 No 0
CACNA1B-203 ENSP00000360406
ENST00000371355
F6RH32
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Show » Show » 2340 262.6 No >9
CACNA1B-204 ENSP00000360416
ENST00000371365
Q5JRE4
Show all »
Show » Show » 164 19 Yes 1
CACNA1B-205 ENSP00000360418
ENST00000371367
Q9HBH2
Show all »
Show » 108 11.9 No 0
CACNA1B-206 ENSP00000441232
ENST00000545473
Q9HAT3
Show all »
Show » Show » 187 20.6 No 0