PARD3

GENERAL INFORMATION

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Gene name

PARD3

Gene description

Par-3 family cell polarity regulator

Protein class

Plasma proteins
Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

13
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Mixed
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Most of the normal tissues displayed weak to moderate cytoplasmic and/or luminal membranous positivity. Bone marrow poetic cells showed strong nuclear staining. Alveolar cells, bile ducts, prostate, cells in CNS, lymphoid tissues and myocytes were generally negative.

ANTIBODY RELIABILITY

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Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA030443
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Mixed

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

PARD3 (HGNC Symbol)

Synonyms

ASIP, Baz, Bazooka, PAR3, PARD3A, PPP1R118

Description

Par-3 family cell polarity regulator (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the PARD protein family. PARD family members interact with other PARD family members and other proteins; they affect asymmetrical cell division and direct polarized cell growth. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Oct 2011]

Chromosome

10

Cytoband

Chromosome location (bp)

34109560 - 34815325

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000148498 (version 78.38)

Entrez gene

56288

UniProt

Q8TEW0 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TEW0

Antibodypedia

PARD3 antibodies


PROTEIN BROWSER

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ENST00000340077
 
ENST00000346874
 
ENST00000350537
 
ENST00000374768
 
ENST00000374773
 
ENST00000374776
 
ENST00000374788
 
ENST00000374789
 
ENST00000374790
 
ENST00000374794
 
ENST00000544292
 
ENST00000545260
 
ENST00000545693
 
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PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PARD3-001 ENSP00000363908
ENST00000374776
Q8TEW0
Show all »
Show » Show » 988 108.5 No 0
PARD3-002 ENSP00000363921
ENST00000374789
Q8TEW0
Show all »
Show » Show » 1356 151.4 No 0
PARD3-003 ENSP00000363920
ENST00000374788
Q8TEW0
Show all »
Show » Show » 1353 151.1 No 0
PARD3-004 ENSP00000340591
ENST00000346874
Q8TEW0
Show all »
Show » Show » 1319 146.9 No 0
PARD3-005 ENSP00000363926
ENST00000374794
Q8TEW0
Show all »
Show » Show » 1244 138.3 No 0
PARD3-006 ENSP00000311986
ENST00000350537
Q8TEW0
Show all »
Show » Show » 1310 146.3 No 0
PARD3-007 ENSP00000363900
ENST00000374768
B1AP52
Show all »
Show » Show » 179 19.3 No 0
PARD3-009 ENSP00000363905
ENST00000374773
Q5VWU8
Show all »
Show » Show » 1001 110 No 0
PARD3-010 ENSP00000363922
ENST00000374790
Q5VWV2
Show all »
Show » Show » 1296 144.5 No 0
PARD3-201 ENSP00000341844
ENST00000340077
Q8TEW0
Show all »
Show » Show » 1031 113.4 No 0
PARD3-202 ENSP00000444429
ENST00000544292
F5GZI3
Show all »
Show » Show » 747 82.1 No 0
PARD3-203 ENSP00000440857
ENST00000545260
Q8TEW0
Show all »
Show » Show » 1266 141.1 No 0
PARD3-204 ENSP00000443147
ENST00000545693
Q8TEW0
Show all »
Show » Show » 1340 149.7 No 0