HABP2

GENE INFORMATION

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Gene name

HABP2 (HGNC Symbol)

Synonyms

FSAP, HABP, HGFAL, PHBP

Description

hyaluronan binding protein 2 (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is an extracellular serine protease that binds hyaluronic acid and is involved in cell adhesion. The encoded protein is synthesized as a single chain, but then undergoes an autoproteolytic event to form the functional heterodimer. Further autoproteolysis leads to smaller, inactive peptides. This protease is known to cleave urinary plasminogen activator, coagulation factor VII, and the alpha and beta chains of fibrinogen, but not prothrombin, plasminogen, or the gamma chain of fibrinogen. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Chromosome

10 (Chromosome progress)

Cytoband

q25.3

Chromosome location (bp)

115310596 - 115349361

Ensembl

ENSG00000148702 (version 73.37)

Entrez gene

3026

UniProt

Q14520 (UniProt - Evidence at protein level)

neXtProt

NX_Q14520

Antibodypedia

HABP2 antibodies
 

PROTEIN VIEW

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HABP2-001
 
HABP2-201
 
HABP2-202
 
HABP2-203
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

HABP2-001 ENSP00000277903
ENST00000351270
Q14520
Show all »
Show » Show » 560 62.7 Yes 0
HABP2-201 ENSP00000446135
ENST00000537906
F5H475
Show all »
177 18.7 No 0
HABP2-202 ENSP00000438373
ENST00000541666
B7Z8Q5
Show all »
Show » Show » 280 31.7 Yes 0
HABP2-203 ENSP00000443283
ENST00000542051
Q14520
Show all »
Show » Show » 534 59.9 No 0