ADAM12

GENE INFORMATION

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Gene name

ADAM12 (HGNC Symbol)

Synonyms

MCMPMltna, MLTN

Description

ADAM metallopeptidase domain 12 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene has two alternatively spliced transcripts: a shorter secreted form and a longer membrane-bound form. The shorter form is found to stimulate myogenesis. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q26.2

Chromosome location (bp)

127700950 - 128077024

Ensembl

ENSG00000148848 (version 73.37)

Entrez gene

8038

UniProt

O43184 (UniProt - Evidence at protein level)

neXtProt

NX_O43184

Antibodypedia

ADAM12 antibodies
 

PROTEIN VIEW

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ADAM12-001
 
ADAM12-002
 
ADAM12-003
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM12-001 ENSP00000357668
ENST00000368679
O43184
Show all »
Show » Show » 909 99.5 Yes 1
ADAM12-002 ENSP00000357665
ENST00000368676
O43184
Show all »
Show » Show » 738 80.4 Yes 0
ADAM12-003 ENSP00000391268
ENST00000448723
Q5JRP2
Show all »
Show » 278 31.1 Yes 0