PAK1

GENE INFORMATION

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Gene name

PAK1

Synonyms

Description

p21 protein (Cdc42/Rac)-activated kinase 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a family member of serine/threonine p21-activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2010]

Chromosome

11 (Chromosome progress)

Cytoband

q13.5

Chromosome location (bp)

77032752 - 77185680

Ensembl

ENSG00000149269 (version 73.37)

Entrez gene

5058

UniProt

Q13153 (UniProt - Evidence at protein level)

neXtProt

NX_Q13153

Antibodypedia

PAK1 antibodies
 

PROTEIN VIEW

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 « 
 
PAK1-001
 
PAK1-002
 
PAK1-003
 
PAK1-004
 
PAK1-006
 
PAK1-007
 
PAK1-009
 
PAK1-010
 
PAK1-011
 
PAK1-014
 
PAK1-018
 
PAK1-019
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

PAK1-001 ENSP00000348696
ENST00000356341
Q13153
Show all »
Show » Show » 545 60.6 No 0
PAK1-002 ENSP00000278568
ENST00000278568
Q13153
Show all »
Show » Show » 553 61.6 No 0
PAK1-003 ENSP00000433423
ENST00000530617
B3KNX7
Show all »
Show » Show » 522 58.2 No 0
PAK1-004 ENSP00000433211
ENST00000528203
E9PM17
Show all »
Show » Show » 455 50.9 No 0
PAK1-006 ENSP00000433737
ENST00000526968
E9PJF8
Show all »
Show » 26 2.8 No 0
PAK1-007 ENSP00000432477
ENST00000524847
E9PQW5
Show all »
Show » 99 10.9 No 0
PAK1-009 ENSP00000433518
ENST00000529248
E9PKH9
Show all »
Show » 106 11.8 No 0
PAK1-010 ENSP00000435983
ENST00000528633
E9PRP6
Show all »
Show » 63 6.8 No 0
PAK1-011 ENSP00000433004
ENST00000528592
E9PMP2
Show all »
Show » 89 9.9 No 0
PAK1-014 ENSP00000431906
ENST00000527457
167 18.5 No 0
PAK1-018 ENSP00000431541
ENST00000533285
Show » Show » 244 27.1 No 0
PAK1-019 ENSP00000437261
ENST00000527535
18 2 No 0