DRD2

GENE INFORMATION

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Gene name

DRD2

Synonyms

Description

dopamine receptor D2 (HGNC Symbol)

Entrez gene summary

This gene encodes the D2 subtype of the dopamine receptor. This G-protein coupled receptor inhibits adenylyl cyclase activity. A missense mutation in this gene causes myoclonus dystonia; other mutations have been associated with schizophrenia. Alternative splicing of this gene results in two transcript variants encoding different isoforms. A third variant has been described, but it has not been determined whether this form is normal or due to aberrant splicing. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q23.2

Chromosome location (bp)

113280318 - 113346413

Ensembl

ENSG00000149295 (version 73.37)

Entrez gene

1813

UniProt

P14416 (UniProt - Evidence at protein level)

neXtProt

NX_P14416

Antibodypedia

DRD2 antibodies
 

PROTEIN VIEW

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DRD2-001
 
DRD2-003
 
DRD2-004
 
DRD2-005
 
DRD2-006
 
DRD2-007
 
DRD2-010
 
DRD2-201
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DRD2-001 ENSP00000354859
ENST00000362072
P14416
Show all »
Show » Show » 443 50.6 No 7
DRD2-003 ENSP00000278597
ENST00000346454
P14416
Show all »
Show » Show » 414 47.3 No 7
DRD2-004 ENSP00000442172
ENST00000542968
P14416
Show all »
Show » Show » 443 50.6 No 7
DRD2-005 ENSP00000441068
ENST00000544518
F8VUV1
Show all »
Show » Show » 442 50.5 No 7
DRD2-006 ENSP00000441474
ENST00000542616
7 0.8 No 0
DRD2-007 ENSP00000438419
ENST00000543292
Q6LDH7
Show all »
Show » Show » 177 20.1 No 4
DRD2-010 ENSP00000438215
ENST00000538967
P14416
Show all »
Show » Show » 445 50.8 No 7
DRD2-201 ENSP00000347474
ENST00000355319
P14416
Show all »
Show » Show » 445 50.8 No 7