GGTLC1

GENERAL INFORMATION

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Gene name

GGTLC1

Gene description

Gamma-glutamyltransferase light chain 1

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

3
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (lung, testis)
GTEx:Group enriched (lung, testis)

Protein evidence

Evidence at protein level

Protein localization

RNA data suggests expression in lung. RNA-based expert annotation gave inconclusive results.

ANTIBODY RELIABILITY

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Data reliability
description

Pending external verification. Caution, targets protein from more than one gene. Presumed off target binding observed and disregarded.

Data reliability

Uncertain based on 2 antibodies.
HPA045635 , HPA047534
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Kidney & urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
N/A
Prostate
N/A
Seminal vesicle
N/A
N/A
Female tissues
N/A
Breast
N/A
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Skin
N/A
Skin
N/A
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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RNA-based expert annotation could not be performed, due to inconclusive results. View immunohistochemistry primary data.


RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (lung, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Group enriched (lung, testis)

Organ

Expression



GENE INFORMATION

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Gene name

GGTLC1 (HGNC Symbol)

Synonyms

dJ831C21.1, dJ831C21.2, GGTLA3, GGTLA4

Description

Gamma-glutamyltransferase light chain 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the gamma-glutamyl transpeptidase (GGT) family, which are important in the metabolism of glutathione. The most ubiquitously expressed human GGT gene, GGT1, encodes a single transmembrane polypeptide that is post-translationally processed to form a heavy and a light chain. In contrast, the product of this gene only contains homology to the light chain region, and lacks a transmembrane domain. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Oct 2008]

Chromosome

20

Cytoband

p11.21

Chromosome location (bp)

23985050 - 23988779

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000149435 (version 78.38)

Entrez gene

92086

UniProt

Q9BX51 (UniProt - Evidence at transcript level)

neXtProt

NX_Q9BX51

Antibodypedia

GGTLC1 antibodies


PROTEIN BROWSER

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ENST00000278765
 
ENST00000286890
 
ENST00000335694
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

GGTLC1-001 ENSP00000278765
ENST00000278765
Q9BX51
Show all »
Show » Show » 225 24.3 No 0
GGTLC1-003 ENSP00000286890
ENST00000286890
Q9BX51
Show all »
Show » Show » 225 24.3 No 0
GGTLC1-006 ENSP00000337587
ENST00000335694
Q9BX51
Show all »
Show » Show » 225 24.3 No 0