FADS1

GENE INFORMATION

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Gene name

FADS1 (HGNC Symbol)

Synonyms

D5D, FADS6, FADSD5, LLCDL1, TU12

Description

Fatty acid desaturase 1 (HGNC Symbol)

Entrez gene summary

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

Chromosome

11

Cytoband

q12.2

Chromosome location (bp)

61567099 - 61596790

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000149485 (version 75.37)

Entrez gene

100302263

UniProt

O60427 (UniProt - Evidence at protein level)

neXtProt

NX_O60427

Antibodypedia

FADS1 antibodies
 

PROTEIN VIEW

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FADS1-001
 
FADS1-002
 
FADS1-004
 
FADS1-005
 
FADS1-006
 
FADS1-007
 
FADS1-008
 
FADS1-009
 
FADS1-010
 
FADS1-012
 
FADS1-013
 
FADS1-014
 
FADS1-016
 
FADS1-017
 
FADS1-018
 
FADS1-019
 
FADS1-020
 
FADS1-022
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FADS1-001 ENSP00000322229
ENST00000350997
O60427
Show all »
Show » Show » 501 57.9 No 5
FADS1-002 ENSP00000405087
ENST00000433932
O60427
Show all »
Show » Show » 360 42.5 No 4
FADS1-004 ENSP00000445253
ENST00000460649
F5H3P6
Show all »
Show » Show » 146 17.3 No 1
FADS1-005 ENSP00000416043
ENST00000421879
C9JJB3
Show all »
Show » Show » 139 16 No 2
FADS1-006 ENSP00000391229
ENST00000448607
C9J425
Show all »
Show » Show » 47 5.4 No 0
FADS1-007 ENSP00000429016
ENST00000491310
I3ZNN6
Show all »
Show » Show » 175 19.7 No 2
FADS1-008 ENSP00000407895
ENST00000424501
F5H1Q7
Show all »
Show » Show » 228 25.4 No 1
FADS1-009 ENSP00000446270
ENST00000466716
F5H2H3
Show all »
Show » Show » 111 12.7 No 2
FADS1-010 ENSP00000445442
ENST00000473263
Show » 16 1.8 No 0
FADS1-012 ENSP00000441403
ENST00000542506
O60427
Show all »
Show » Show » 360 42.5 No 4
FADS1-013 ENSP00000443587
ENST00000539999
F5H8G5
Show all »
Show » Show » 124 15.3 No 2
FADS1-014 ENSP00000439790
ENST00000544309
F5H0Y2
Show all »
Show » Show » 109 12.4 No 2
FADS1-016 ENSP00000441871
ENST00000540767
F5GWE3
Show all »
Show » Show » 165 19 No 2
FADS1-017 ENSP00000443037
ENST00000544696
F5H5X5
Show all »
Show » Show » 112 12.8 No 2
FADS1-018 ENSP00000440652
ENST00000545405
F5GYH4
Show all »
Show » Show » 153 17.7 No 2
FADS1-019 ENSP00000442170
ENST00000545245
F5H852
Show all »
Show » Show » 164 18.9 No 2
FADS1-020 ENSP00000438997
ENST00000539419
F5H1Q7
Show all »
Show » Show » 86 9.8 No 1
FADS1-022 ENSP00000439097
ENST00000536991
F5H3U5
Show all »
Show » Show » 192 22.7 Yes 3