EI24

GENE INFORMATION

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Gene name

EI24 (HGNC Symbol)

Synonyms

EPG4, PIG8, TP53I8

Description

etoposide induced 2.4 (HGNC Symbol)

Entrez gene summary

This gene has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The protein encoded by this gene contains six putative transmembrane domains and may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

Chromosome

11 (Chromosome progress)

Cytoband

q24.2

Chromosome location (bp)

125439112 - 125454575

Ensembl

ENSG00000149547 (version 73.37)

Entrez gene

9538

UniProt

O14681 (UniProt - Evidence at protein level)

neXtProt

NX_O14681

Antibodypedia

EI24 antibodies
 

PROTEIN VIEW

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EI24-007
 
EI24-008
 
EI24-009
 
EI24-011
 
EI24-013
 
EI24-015
 
EI24-201
 
EI24-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

EI24-007 ENSP00000436130
ENST00000529812
14 1.6 No 0
EI24-008 ENSP00000433376
ENST00000527131
E9PL33
Show all »
Show » Show » 125 14.6 No 1
EI24-009 ENSP00000435034
ENST00000527842
E9PM05
Show all »
Show » Show » 187 21.6 No 3
EI24-011 ENSP00000435923
ENST00000524723
E9PS58
Show all »
Show » 217 25.1 No 2
EI24-013 ENSP00000435225
ENST00000527520
E9PLB8
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Show » 91 10.8 No 1
EI24-015 ENSP00000431633
ENST00000527235
E9PK61
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41 4.8 No 0
EI24-201 ENSP00000278903
ENST00000278903
O14681
Show all »
Show » Show » 339 38.9 No 6
EI24-202 ENSP00000364081
ENST00000343678
A6NES3
Show all »
Show » Show » 261 30 No 4