MRPL49

GENE INFORMATION

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Gene name

MRPL49 (HGNC Symbol)

Synonyms

C11orf4, L49mt, NOF, NOF1

Description

mitochondrial ribosomal protein L49 (HGNC Symbol)

Entrez gene summary

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to this gene are found on chromosomes 5q and 8p. [provided by RefSeq, May 2011]

Chromosome

11 (Chromosome progress)

Cytoband

q13.1

Chromosome location (bp)

64889655 - 64894843

Ensembl

ENSG00000149792 (version 73.37)

Entrez gene

740

UniProt

Q13405 (UniProt - Evidence at protein level)

neXtProt

NX_Q13405

Antibodypedia

MRPL49 antibodies
 

PROTEIN VIEW

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MRPL49-001
 
MRPL49-004
 
MRPL49-005
 
MRPL49-006
 
MRPL49-008
 
MRPL49-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

MRPL49-001 ENSP00000279242
ENST00000279242
Q13405
Show all »
Show » Show » 166 19.2 No 0
MRPL49-004 ENSP00000434190
ENST00000526319
Q13405
Show all »
Show » Show » 166 19.2 No 0
MRPL49-005 ENSP00000434052
ENST00000533943
Show » 127 14.6 No 0
MRPL49-006 ENSP00000437177
ENST00000526171
E9PNF1
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Show » 140 16 No 0
MRPL49-008 ENSP00000434222
ENST00000534078
E9PRD2
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56 6.1 No 0
MRPL49-009 ENSP00000436740
ENST00000531705
E9PI78
Show all »
Show » 99 11.3 No 0