ALDOA

GENE INFORMATION

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Gene name

ALDOA

Synonyms

Description

aldolase A, fructose-bisphosphate (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene, Aldolase A (fructose-bisphosphate aldolase), is a glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Three aldolase isozymes (A, B, and C), encoded by three different genes, are differentially expressed during development. Aldolase A is found in the developing embryo and is produced in even greater amounts in adult muscle. Aldolase A expression is repressed in adult liver, kidney and intestine and similar to aldolase C levels in brain and other nervous tissue. Aldolase A deficiency has been associated with myopathy and hemolytic anemia. Alternative splicing and alternative promoter usage results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 3 and 10. [provided by RefSeq, Aug 2011]

Chromosome

16 (Chromosome progress)

Cytoband

p11.2

Chromosome location (bp)

30064411 - 30081778

Ensembl

ENSG00000149925 (version 73.37)

Entrez gene

226

UniProt

P04075 (UniProt - Evidence at protein level)

neXtProt

NX_P04075

Antibodypedia

ALDOA antibodies
 

PROTEIN VIEW

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ALDOA-001
 
ALDOA-002
 
ALDOA-003
 
ALDOA-004
 
ALDOA-005
 
ALDOA-006
 
ALDOA-007
 
ALDOA-008
 
ALDOA-009
 
ALDOA-010
 
ALDOA-011
 
ALDOA-017
 
ALDOA-019
 
ALDOA-020
 
ALDOA-022
 
ALDOA-028
 
ALDOA-030
 
 » 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ALDOA-001 ENSP00000455917
ENST00000564546
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-002 ENSP00000378669
ENST00000395248
P04075
Show all »
Show » Show » 418 45.3 Yes 0
ALDOA-003 ENSP00000457683
ENST00000568435
12 1.4 No 0
ALDOA-004 ENSP00000455724
ENST00000566897
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-005 ENSP00000336927
ENST00000338110
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-006 ENSP00000455800
ENST00000563060
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-007 ENSP00000455700
ENST00000569545
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-008 ENSP00000400452
ENST00000412304
P04075
Show all »
Show » Show » 364 39.4 No 0
ALDOA-009 ENSP00000457468
ENST00000564595
P04075
Show all »
Show » Show » 418 45.3 Yes 0
ALDOA-010 ENSP00000455857
ENST00000569798
H3BQN4
Show all »
Show » 361 39.3 No 0
ALDOA-011 ENSP00000378661
ENST00000395240
J3KPS3
Show all »
Show » 368 39.8 No 0
ALDOA-017 ENSP00000456020
ENST00000562168
H3BR04
Show all »
Show » 162 17.8 No 0
ALDOA-019 ENSP00000455455
ENST00000562679
H3BPS8
Show all »
Show » 278 30.4 Yes 0
ALDOA-020 ENSP00000457643
ENST00000563987
H3BUH7
Show all »
Show » 155 16.9 No 0
ALDOA-022 ENSP00000457514
ENST00000564688
H3BU78
Show all »
Show » 204 22.1 No 0
ALDOA-028 ENSP00000456098
ENST00000565355
Show » 130 13.7 No 0
ALDOA-030 ENSP00000454499
ENST00000566846
H3BMQ8
Show all »
Show » 140 15.5 No 0