CNDP1

GENERAL INFORMATION

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Gene name

CNDP1

Gene description

Carnosine dipeptidase 1 (metallopeptidase M20 family)

Protein class

Enzymes
Plasma proteins
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Group enriched (cerebral cortex, liver)
GTEx:Tissue enhanced (cerebral cortex, hippocampus)

Protein evidence

Evidence at protein level

Protein localization

Distinct expression in CNS and positivity in plasma.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly consistent with RNA expression data. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.

Data reliability

Supportive based on 1 antibody.
HPA008933
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Group enriched (cerebral cortex, liver)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (cerebral cortex, hippocampus)

Organ

Expression



GENE INFORMATION

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Gene name

CNDP1 (HGNC Symbol)

Synonyms

CN1, CPGL2, HsT2308, MGC10825

Description

Carnosine dipeptidase 1 (metallopeptidase M20 family) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the M20 metalloprotease family. The encoded protein is specifically expressed in the brain, is a homodimeric dipeptidase which was identified as human carnosinase. This gene contains trinucleotide (CTG) repeat length polymorphism in the coding region. [provided by RefSeq, Jul 2008]

Chromosome

18

Cytoband

q22.3

Chromosome location (bp)

74534440 - 74587212

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150656 (version 78.38)

Entrez gene

84735

UniProt

Q96KN2 (UniProt - Evidence at protein level)

neXtProt

NX_Q96KN2

Antibodypedia

CNDP1 antibodies


PROTEIN BROWSER

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ENST00000358821
 
ENST00000582365
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CNDP1-001 ENSP00000351682
ENST00000358821
Q96KN2
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Show » Show » 507 56.7 Yes 0
CNDP1-004 ENSP00000462096
ENST00000582365
Show » Show » 464 51.9 No 0