IL18

GENE INFORMATION

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Gene name

IL18 (HGNC Symbol)

Synonyms

IGIF, IL-18, IL-1g, IL1F4

Description

Interleukin 18 (interferon-gamma-inducing factor) (HGNC Symbol)

Entrez gene summary

The protein encoded by this gene is a proinflammatory cytokine that augments natural killer cell activity in spleen cells, and stimulates interferon gamma production in T-helper type I cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

Chromosome

11

Cytoband

q23.1

Chromosome location (bp)

112013974 - 112034840

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000150782 (version 75.37)

Entrez gene

3606

UniProt

Q14116 (UniProt - Evidence at protein level)

neXtProt

NX_Q14116

Antibodypedia

IL18 antibodies
 

PROTEIN VIEW

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IL18-001
 
IL18-003
 
IL18-006
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

IL18-001 ENSP00000280357
ENST00000280357
Q14116
Show all »
Show » Show » 193 22.3 No 0
IL18-003 ENSP00000434561
ENST00000524595
Q14116
Show all »
Show » Show » 189 21.9 No 0
IL18-006 ENSP00000434161
ENST00000528832
Q14116
Show all »
Show » Show » 193 22.3 No 0