KCNA6

GENE INFORMATION

? »

Gene name

KCNA6 (HGNC Symbol)

Synonyms

HBK2, Kv1.6

Description

potassium voltage-gated channel, shaker-related subfamily, member 6 (HGNC Symbol)

Entrez gene summary

Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008]

Chromosome

12 (Chromosome progress)

Cytoband

p13.32

Chromosome location (bp)

4918342 - 4960277

Ensembl

ENSG00000151079 (version 73.37)

Entrez gene

3742

UniProt

P17658 (UniProt - Evidence at protein level)

neXtProt

NX_P17658

Antibodypedia

KCNA6 antibodies
 

PROTEIN VIEW

? »
 
 
 
KCNA6-001
 
KCNA6-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

KCNA6-001 ENSP00000280684
ENST00000280684
P17658
Show all »
Show » Show » 529 58.7 No 5
KCNA6-201 ENSP00000408321
ENST00000433855
P17658
Show all »
Show » Show » 529 58.7 No 5