DLG5

GENE INFORMATION

? »

Gene name

DLG5 (HGNC Symbol)

Synonyms

KIAA0583, P-dlg

Description

discs, large homolog 5 (Drosophila) (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the family of discs large (DLG) homologs, a subset of the membrane-associated guanylate kinase (MAGUK) superfamily. The MAGUK proteins are composed of a catalytically inactive guanylate kinase domain, in addition to PDZ and SH3 domains, and are thought to function as scaffolding molecules at sites of cell-cell contact. The protein encoded by this gene localizes to the plasma membrane and cytoplasm, and interacts with components of adherens junctions and the cytoskeleton. It is proposed to function in the transmission of extracellular signals to the cytoskeleton and in the maintenance of epithelial cell structure. Alternative splice variants have been described but their biological nature has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

10 (Chromosome progress)

Cytoband

q22.3

Chromosome location (bp)

79550549 - 79686378

Ensembl

ENSG00000151208 (version 73.37)

Entrez gene

9231

UniProt

Q8TDM6 (UniProt - Evidence at protein level)

neXtProt

NX_Q8TDM6

Antibodypedia

DLG5 antibodies
 

PROTEIN VIEW

? »
 
 
 
DLG5-001
 
DLG5-002
 
DLG5-005
 
DLG5-201
 
 
 
 
 

PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

DLG5-001 ENSP00000361467
ENST00000372391
Q8TDM6
Show all »
Show » Show » 1919 213.9 No 0
DLG5-002 ENSP00000473298
ENST00000468332
R4GMQ2
Show all »
214 24.6 No 0
DLG5-005 ENSP00000394797
ENST00000424842
Q8TDM6
Show all »
Show » Show » 880 96.7 No 0
DLG5-201 ENSP00000361464
ENST00000372388
Q8TDM6
Show all »
Show » Show » 1579 177 No 0