ATP6V1G3

GENE INFORMATION

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Gene name

ATP6V1G3 (HGNC Symbol)

Synonyms

ATP6G3, Vma10

Description

ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G3 (HGNC Symbol)

Entrez gene summary

This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'' and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This gene encodes one of three G subunit proteins. Transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

1 (Chromosome progress)

Cytoband

q31.3

Chromosome location (bp)

198492352 - 198510075

Ensembl

ENSG00000151418 (version 73.37)

Entrez gene

127124

UniProt

Q96LB4 (UniProt - Evidence at transcript level)

neXtProt

NX_Q96LB4

Antibodypedia

ATP6V1G3 antibodies
 

PROTEIN VIEW

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ATP6V1G3-001
 
ATP6V1G3-002
 
ATP6V1G3-003
 
ATP6V1G3-201
 
ATP6V1G3-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ATP6V1G3-001 ENSP00000356352
ENST00000367382
Q96LB4
Show all »
Show » Show » 118 13.9 No 0
ATP6V1G3-002 ENSP00000309574
ENST00000309309
Q96LB4
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Show » Show » 59 6.9 No 0
ATP6V1G3-003 ENSP00000417171
ENST00000489986
Q96LB4
Show all »
Show » Show » 124 14.4 No 0
ATP6V1G3-201 ENSP00000281087
ENST00000281087
Q96LB4
Show all »
Show » Show » 118 13.9 No 0
ATP6V1G3-202 ENSP00000356351
ENST00000367381
Q96LB4
Show all »
Show » Show » 124 14.4 No 0