AKR1C2

TISSUE ATLAS

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Gene description

Aldo-keto reductase family 1, member C2

RNA tissue category

Mixed.

Protein summary

Detected at High or Medium expression level in 8 of 74 analyzed normal tissue cell types.

Protein expression

Strong cytoplasmic and nuclear positivity was observed in hepatocytes, urinary bladder and stomach. A subset of glandular cells in small intestine and exocrine glandular cells in pancreas along with oral mucosa, esophagus, nasopharynx and Leydig cells were moderately stained. Remaining normal tissues were in general negative.

Protein class

Enzymes

Protein evidence

High

Protein reliability

Supportive based on 1 antibody.
Liver
Colon
Kidney
Testis
Lymph node
Cerebral cortex
Urinary bladder
RNA Protein

Expression (FPKM)

Organ system

Localization (score)

300
150
0

h
m
l
n

Liver and pancreas
Liver
Gallbladder N/A
Pancreas
Digestive tract (GI-tract)
N/A Oral mucosa
Salivary gland
Esophagus
Stomach
Duodenum
Small intestine
Appendix
Colon
N/A Rectum
Urinary tract (Kidney and bladder)
Kidney
Urinary bladder
Male reproductive system (Male tissues)
Testis
N/A Epididymis
Prostate
N/A Seminal vesicle
Breast and female reproductive system
N/A Breast
N/A Vagina N/A
N/A Cervix, uterine
Uterus
N/A Fallopian tube
Ovary
Placenta
Skin and soft tissues
Adipose tissue
Skin
N/A Skeletal muscle
N/A Smooth muscle
N/A Soft tissue
Blood and immune system (Hematopoietic)
Bone marrow
Lymph node
N/A Tonsil
Spleen
Central nervous system (Brain)
Cerebral cortex
N/A Hippocampus
N/A Lateral ventricle
N/A Cerebellum
Endocrine glands
Thyroid gland
N/A Parathyroid gland
Adrenal gland
Respiratory system (Lung)
N/A Nasopharynx
N/A Bronchus
Lung
Cardiovascular system
Heart muscle

Antibodies in assay

CAB047304