ADAM8

GENE INFORMATION

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Gene name

ADAM8 (HGNC Symbol)

Synonyms

CD156, MS2

Description

ADAM metallopeptidase domain 8 (HGNC Symbol)

Entrez gene summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2009]

Chromosome

10 (Chromosome progress)

Cytoband

q26.3

Chromosome location (bp)

135075907 - 135090372

Ensembl

ENSG00000151651 (version 73.37)

Entrez gene

101

UniProt

P78325 (UniProt - Evidence at protein level)

neXtProt

NX_P78325

Antibodypedia

ADAM8 antibodies
 

PROTEIN VIEW

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ADAM8-001
 
ADAM8-004
 
ADAM8-005
 
ADAM8-007
 
ADAM8-009
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ADAM8-001 ENSP00000453302
ENST00000445355
P78325
Show all »
Show » Show » 824 88.8 Yes 1
ADAM8-004 ENSP00000453735
ENST00000486609
H0YMT6
Show all »
Show » 245 26.9 Yes 0
ADAM8-005 ENSP00000453043
ENST00000485491
P78325
Show all »
Show » Show » 733 78.8 Yes 1
ADAM8-007 ENSP00000452994
ENST00000560135
H0YKZ1
Show all »
109 11.7 Yes 0
ADAM8-009 ENSP00000453855
ENST00000415217
P78325
Show all »
Show » Show » 742 80.3 Yes 0