FLI1

GENE INFORMATION

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Gene name

FLI1 (HGNC Symbol)

Synonyms

EWSR2, SIC-1

Description

Friend leukemia virus integration 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11;22)(q24;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4;11)(q21;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]

Chromosome

11 (Chromosome progress)

Cytoband

q24.3

Chromosome location (bp)

128555046 - 128683161

Ensembl

ENSG00000151702 (version 73.37)

Entrez gene

2313

UniProt

Q01543 (UniProt - Evidence at protein level)

neXtProt

NX_Q01543

Antibodypedia

FLI1 antibodies
 

PROTEIN VIEW

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FLI1-001
 
FLI1-002
 
FLI1-003
 
FLI1-004
 
FLI1-201
 
FLI1-202
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

FLI1-001 ENSP00000399985
ENST00000429175
Q01543
Show all »
Show » Show » 452 51 No 0
FLI1-002 ENSP00000433488
ENST00000527786
E9PKJ7
Show all »
Show » 82 9.1 No 0
FLI1-003 ENSP00000432950
ENST00000534087
Q01543
Show all »
Show » Show » 419 47.6 No 0
FLI1-004 ENSP00000437124
ENST00000525560
Q01543
Show all »
Show » Show » 259 29.1 No 0
FLI1-201 ENSP00000281428
ENST00000281428
Q01543
Show all »
Show » Show » 386 43.6 No 0
FLI1-202 ENSP00000339627
ENST00000344954
Q01543
Show all »
Show » Show » 419 47.6 No 0