G6PC2

GENE INFORMATION

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Gene name

G6PC2 (HGNC Symbol)

Synonyms

IGRP

Description

glucose-6-phosphatase, catalytic, 2 (HGNC Symbol)

Entrez gene summary

This gene encodes an enzyme belonging to the glucose-6-phosphatase catalytic subunit family. These enzymes are part of a multicomponent integral membrane system that catalyzes the hydrolysis of glucose-6-phosphate, the terminal step in gluconeogenic and glycogenolytic pathways, allowing the release of glucose into the bloodstream. The family member encoded by this gene is found in pancreatic islets and does not exhibit phosphohydrolase activity, but it is a major target of cell-mediated autoimmunity in diabetes. Several alternatively spliced transcript variants of this gene have been described, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]

Chromosome

2 (Chromosome progress)

Cytoband

q31.1

Chromosome location (bp)

169757750 - 169766505

Ensembl

ENSG00000152254 (version 73.37)

Entrez gene

57818

UniProt

Q9NQR9 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NQR9

Antibodypedia

G6PC2 antibodies
 

PROTEIN VIEW

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G6PC2-001
 
G6PC2-002
 
G6PC2-004
 
G6PC2-005
 
 
 
 
 

PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

G6PC2-001 ENSP00000364512
ENST00000375363
Q9NQR9
Show all »
Show » Show » 355 40.6 No 8
G6PC2-002 ENSP00000282075
ENST00000282075
Q9NQR9
Show all »
Show » Show » 102 12.2 No 0
G6PC2-004 ENSP00000396939
ENST00000429379
Q9NQR9
Show all »
Show » Show » 154 17.8 No 2
G6PC2-005 ENSP00000392183
ENST00000421979
C9IYU7
Show all »
Show » 80 9.5 No 0