SH2D6

GENERAL INFORMATION

? »

Gene name

SH2D6

Gene description

SH2 domain containing 6

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

? »

RNA tissue category

HPA:Tissue enhanced (duodenum, testis)
GTEx:Tissue enhanced (colon, testis)

Protein evidence

Evidence at transcript level

Protein localization

Hematopoietic cells, renal tubules, hepatocytes, fibroblasts and Leydig cells displayed strong cytoplasmic staining. Adrenocortical cells, gastrointestinal tract and pneumocytes exhibited moderate cytoplasmic positivity with additional membranous staining in few tissues. Remaining normal tissues were weakly stained or negative.

ANTIBODY RELIABILITY

? »

Data reliability
description

Pending RNA-based expert annotation.

Data reliability

Uncertain based on 1 antibody.
HPA053873
SHOW MORE

RNA AND PROTEIN EXPRESSION SUMMARY

? »
RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

? »

Organ

Expression



RNA EXPRESSION OVERVIEW

? »
HPA dataset
RNA tissue category:  Tissue enhanced (duodenum, testis)

Organ

Expression

GTEx dataset
RNA tissue category:  Tissue enhanced (colon, testis)

Organ

Expression



GENE INFORMATION

? »

Gene name

SH2D6 (HGNC Symbol)

Synonyms

FLJ35993

Description

SH2 domain containing 6 (HGNC Symbol)

Entrez gene summary

Chromosome

2

Cytoband

p11.2

Chromosome location (bp)

85418721 - 85437029

Protein evidence

Evidence at transcript level (all genes)

Ensembl

ENSG00000152292 (version 78.38)

Entrez gene

284948

UniProt

Q7Z4S9 (UniProt - Evidence at transcript level)

neXtProt

NX_Q7Z4S9

Antibodypedia

SH2D6 antibodies


PROTEIN BROWSER

? »
 
 
 
ENST00000340326
 
ENST00000389938
 
 
 
 


PROTEIN INFORMATION

? »

Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

SH2D6-001 ENSP00000341867
ENST00000340326
Q7Z4S9
Show all »
Show » 175 19.3 No 0
SH2D6-002 ENSP00000374588
ENST00000389938
Q7Z4S9
Show all »
Show » 143 15.4 No 0