ANAPC1

GENERAL INFORMATION

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Gene name

ANAPC1

Gene description

Anaphase promoting complex subunit 1

Protein class

Cancer-related genes
Predicted membrane proteins

Predicted localization

Membrane

Number of transcripts

2
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HUMAN PROTEIN ATLAS INFORMATION

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RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all

Protein evidence

Evidence at protein level

Protein localization

Cytoplasmic expression in several tissue types, most abundant in gastrointestinal tract.

ANTIBODY RELIABILITY

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Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Data reliability

Uncertain based on 3 antibodies.
HPA036329 , HPA036330 , HPA042998
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RNA AND PROTEIN EXPRESSION SUMMARY

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RNA expression (FPKM) Protein expression (score)
Brain
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Pancreas

Colon

Kidney

Testis



PROTEIN EXPRESSION OVERVIEW

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Organ

Expression



RNA EXPRESSION OVERVIEW

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HPA dataset
RNA tissue category:  Expressed in all

Organ

Expression

GTEx dataset
RNA tissue category:  Expressed in all

Organ

Expression



GENE INFORMATION

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Gene name

ANAPC1 (HGNC Symbol)

Synonyms

APC1, MCPR, TSG24

Description

Anaphase promoting complex subunit 1 (HGNC Symbol)

Entrez gene summary

This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]

Chromosome

2

Cytoband

q13

Chromosome location (bp)

111766271 - 111884690

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000153107 (version 78.38)

Entrez gene

64682

UniProt

Q9H1A4 (UniProt - Evidence at protein level)

neXtProt

NX_Q9H1A4

Antibodypedia

ANAPC1 antibodies


PROTEIN BROWSER

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ENST00000341068
 
ENST00000427997
 
 
 
 


PROTEIN INFORMATION

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Splice variant

Ensembl

UniProt

Protein class

Gene ontology

Length
(aa)

Molecular mass
(kDa)

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ANAPC1-001 ENSP00000339109
ENST00000341068
Q9H1A4
Show all »
Show » Show » 1944 216.5 No 1
ANAPC1-005 ENSP00000396695
ENST00000427997
Show » 1452 161.5 No 1